KMID : 1160420220040020057
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Epilia: Epilepsy Commun 2022 Volume.4 No. 2 p.57 ~ p.62
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Statins in Epilepsy: From Mechanisms to Evidence
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Park Kyung-Il
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Abstract
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While statins were developed as drugs to suppress cholesterol synthesis, they also prevent vascular diseases as off-target effects. Numerous experimental and clinical studies have proven that statins could be beneficial for reducing ictogenesis and epileptogenesis. We aimed to summarize and elaborate on up-to-date evidence of the role of statins in epilepsy and consider the mechanisms responsible for their beneficial effects.
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KEYWORD
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Statin, Epileptogenesis, Ictogenesis, Pharmacology, Poststroke epilepsy
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